The role of hormones in hair loss

Hormones play an important role in hair loss, particularly in androgenetic alopecia, which is the most common cause of hair loss in both men and women. Androgenetic alopecia is caused by a combination of genetics and hormones, specifically dihydrotestosterone (DHT).

DHT is a hormone that is produced by the conversion of testosterone by an enzyme called 5-alpha-reductase. Hair follicles that are genetically predisposed to be sensitive to DHT will shrink and produce weaker, thinner hair over time. This leads to a progressive miniaturization of hair follicles and eventually hair loss.

In women, hormonal changes during pregnancy, menopause, and the use of birth control pills can also contribute to hair loss. During pregnancy, increased levels of estrogen can prolong the growth phase of the hair cycle, resulting in thicker, fuller hair. However, after childbirth, estrogen levels drop, and hair may enter the resting phase prematurely, resulting in increased hair shedding.

In menopausal women, declining estrogen levels can lead to thinning hair and increased shedding. Androgenic hormones, such as testosterone, can also increase in women during menopause, leading to hair loss.

Other medical conditions that affect hormone levels, such as thyroid disorders or polycystic ovary syndrome (PCOS), can also contribute to hair loss.

It’s important to speak with a healthcare provider or a dermatologist to determine the underlying cause of hair loss and develop a treatment plan that is tailored to your individual needs. Treatment options may include medications that block the effects of DHT or hormone replacement therapy to restore hormonal balance.